Ozone therapy is available to promote wound relieve by improving circulation, increase oxygen levels in cells, and stimulating the immune system. Additionally, it may help reduce inflammation (Cleveland Clinic).

There is some evidence that Ozone treatment is effective controlling pain, infections, inflammation and wound healing (Brazilian Unified Health System).

Short-term ozone therapy is effective in promoting wound healing reducing inflammation, improving oxidative stress, shortening healing time, and improving long-term prognosis (Diabetic foot ulcers).